Novel compounds advantageous in the treatment of central nervous system...
A series of novel compounds showing anticonvulsant, chemical countermeasure(s), and analgesic activities is described. Such pharmaceutically active compounds may also show utility in the treatment of...
View ArticleNovel compounds advantageous in the treatment of central nervous system...
A series of novel compounds showing anticonvulsant activity is described. Such pharmaceutically active compounds may also show utility in the treatment of other central nervous system (“CNS”) diseases...
View ArticlePhospholipase a2 inhibitors and their use in treating neurological injury and...
Phospholipase A2 (PLA2) forms are expressed in spinal cord whose inhibition induces a potent antihyperalgesia. PLA2 inhibitor compounds are provided that include a common motif consisting of a...
View ArticlePerlecan domain v protects, repairs and restores ischemic brain stroke injury...
The disclosed invention relates to the use of perlecan domain V (DV) for the treatment of stroke, traumatic brain injury (TBI) or spinal cord injuries (SCI). In certain embodiments, fusion proteins of...
View ArticleTherapeutic agent for spinal cord injuries
Disclosed is a therapeutic agent effective for the fundamental treatment of a spinal cord injury and a demyelinating disease. Specifically disclosed are a therapeutic agent for a spinal cord injury...
View ArticleIdentification, diagnosis, and treatment of neuropathologies,...
The present invention relates to devices and methods of use thereof for detection of biomolecules, in vitro, in vivo, or in situ. The invention relates to methods of diagnosing and/or treating a...
View ArticlePharmaceutical compositions for intranasal administration for the treatment...
In one embodiment of the invention, a pharmaceutical composition for intranasal administration comprises insulin, dimethyl sulfoxide and at least one pharmaceutically acceptable excipient. In another...
View ArticleMethod for treating neuropathic pain
Provided is a method for treating neuropathic pain, including: providing, to a patient suffering from said neuropathic pain, a visual illusion to correct a mismatch between motor commands and sensory...
View ArticleApparatus to be worn on an individual's chest below a full face helmet to...
An apparatus to be worn on an individual's shoulders, chest and back below a full face helmet to limit the occurrence of cervical spinal cord injuries in the event of a crash....
View ArticleHand rehabilitation device
A hand rehabilitation device (), used in rehabilitation therapies of the motility and functionality of metacarpus-phalanx, proximal interphalanx and distal interphalanx joints, injured or reduced...
View ArticleMethod for inhibiting the induction of cell death by inhibiting the synthesis...
The present invention relates to a method for inhibiting the induction of cell death by inhibiting the synthesis or secretion of AGE-albumin in cells of the mononuclear phagocyte system, to an...
View ArticleMethods and compositions for the treatment of open and closed wound spinal...
Devices and methods for the treatment of open and closed wound spinal cord injuries are disclosed. For example, described herein are devices and methods for mitigating secondary injury to, and...
View ArticleTreating spinal cord injuries via laser therapy
Aspects for treating spinal cord injuries are disclosed. In a particular aspect, a method includes identifying a neurological level of a spinal cord injury, and activating neurons via laser therapy in...
View ArticleMethod for regulating neurite growth
This invention relates to a method of inhibiting neuronal cell death, including protecting neuronal cells from cell death and the effects of stress, such as high or low pH, comprising administering to...
View ArticleNovel use for imidazotriazinones
Provided herein are compounds for use in the treatment of central nervous system (CNS)-trauma related disorders like spinal cord injuries. Pharmaceutical compositions, single unit dosage forms, and...
View ArticleBipolar spinal cord stimulation to activate the expiratory muscles to restore...
Methods and devices are provided for electrical stimulation of the expiratory muscles in humans or other mammals to produce cough in patients with spinal cord injuries resulting in paralysis of the...
View ArticleNovel use of benzofuranylsulfonates
Provided herein are compounds for use in the treatment of central nervous system (CNS)-trauma related disorders like spinal cord injuries. Pharmaceutical compositions, single unit dosage forms, and...
View ArticleTreating spinal cord injuries via laser therapy
Aspects for treating spinal cord injuries are disclosed. In a particular aspect, a method includes identifying a neurological level of a spinal cord injury, and activating neurons via laser therapy in...
View ArticleMethods and compositions for the treatment of open and closed wound spinal...
Devices and methods for the treatment of open and closed wound spinal cord injuries are disclosed. For example, described herein are devices and methods for mitigating secondary injury to, and...
View ArticleUse of minocycline for therapeutic treatment of acute spinal cord injuries
A dosing regime for providing therapy for a neurological trauma such as spinal cord injury in a human subject. The dosing regime comprises intravenous administration of a plurality of minocycline...
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